2,6-Dichloroimidazo[1,2-a]pyridine CAS 112581-60-9

Purity 97%+In StockPharmaceutical Standards
CAS No.112581-60-9
Molecular FormulaC7H4Cl2N2
Molecular Weight187.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Dichloroimidazo[1,2-a]pyridine CAS 112581-60-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,6-Dichloroimidazo[1,2-a]pyridine.

CATO supplies 2,6-Dichloroimidazo[1,2-a]pyridine (CAS 112581-60-9), a certified reference material (molecular formula C7H4Cl2N2, MW 187.03 g/mol) for analytical method development and quality control.

The molecular framework of 2,6-Dichloroimidazo[1,2-a]pyridine (C7H4Cl2N2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,6-Dichloroimidazo[1,2-a]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H4Cl2N2
Molecular Weight187.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms2

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