3-Benzoyl-7-methyl-2-(methylthio)indolizine-1-carbonitrile CAS 112586-22-8

Purity 97%+In StockPharmaceutical Standards
CAS No.112586-22-8
Molecular FormulaC18H14N2OS
Molecular Weight306.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Benzoyl-7-methyl-2-(methylthio)indolizine-1-carbonitrile CAS 112586-22-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Benzoyl-7-methyl-2-(methylthio)indolizine-1-carbonitrile.

CATO supplies 3-Benzoyl-7-methyl-2-(methylthio)indolizine-1-carbonitrile (CAS 112586-22-8), a certified reference material (molecular formula C18H14N2OS, MW 306.38 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, 3-Benzoyl-7-methyl-2-(methylthio)indolizine-1-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 306.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H14N2OS
Molecular Weight306.38 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms2
Sulfur Atoms1

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