8-fluoronaphthalene-1-carbaldehyde CAS 112641-28-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-fluoronaphthalene-1-carbaldehyde.

CATO supplies 8-fluoronaphthalene-1-carbaldehyde (CAS 112641-28-8), a certified reference material (molecular formula C11H17FO, MW 184.25 g/mol) for analytical method development and quality control.

The molecular framework of 8-fluoronaphthalene-1-carbaldehyde (C11H17FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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