(D-Leu6)-LHRH (1-8) (free acid) trifluoroacetate salt CAS 112642-14-5
| CAS No. | 112642-14-5 |
| Molecular Formula | C52H72N14O12 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (D-Leu6)-LHRH (1-8) (free acid) trifluoroacetate salt.
(D-Leu6)-LHRH (1-8) (free acid) trifluoroacetate salt (CAS 112642-14-5), molecular formula C52H72N14O12C2HF3O2 and molecular weight 1199.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (D-Leu6)-LHRH (1-8) (free acid) trifluoroacetate salt (C52H72N14O12C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (D-Leu6)-LHRH (1-8) (free acid) trifluoroacetate salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C52H72N14O12 C2HF3O2 |
| Molecular Weight | 1199.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 14 |
Recommended Standards
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- 3-(4-bromothiophen-2-yl)-2-oxopropanoic acid (CAS 1155083-00-3)
- 2-Oxo-1,2-dihydroquinoline-6-carbonitrile (CAS 63124-11-8)
- 944890-94-2 2-Bromo-N-(6-methoxy-1,3-benzothiazol-2-yl)-2-methylpropanamide MFCD09755223 (CAS 944890-94-2)
- BisEDT (CAS 175880-68-9)
- 2-Isopropyl-3-methoxy-5-methylpyrazine (CAS 56343-37-4)
- 2-Cyano-N-(4-ethylphenyl)acetamide (CAS 340304-99-6)
- (R)-3-Amino-3-(m-tolyl)propanoicacid (CAS 748128-33-8)
- 8-Ethyl-4-(3-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-69-8)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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