2-Hydroxy Imiquimod CAS 112668-45-8
| CAS No. | 112668-45-8 |
| Molecular Formula | C14H16N4O |
| Molecular Weight | 256.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Hydroxy Imiquimod.
CATO supplies 2-Hydroxy Imiquimod (CAS 112668-45-8), a certified reference material (molecular formula C14H16N4O, MW 256.30 g/mol) for analytical method development and quality control.
Structurally, 2-Hydroxy Imiquimod (C14H16N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 256.30 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N4O |
| Molecular Weight | 256.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Hydroxy Standards
- Benzyl 4-hydroxy-3,5-dimethylbenzoate (CAS 115853-69-5)
- 3-Hydroxy Imiquimod; (CAS 1807606-78-5)
- (2S)-4’-Hydroxy-7-methoxyflavan (CAS 27348-54-5)
- (E)-3-Hydroxy-4',5-dimethoxystilbene (CAS 58436-29-6)
- 1-(2-Hydroxy-4-((4-methylbenzyl)oxy)phenyl)ethan-1-one (CAS 885949-75-7)
- 1-(2-Hydroxy-4-methoxyphenyl)-2-(p-tolyl)ethan-1-one (CAS 474391-07-6)
- 2-Hydroxy-6-phenethyl-benzoic acid methyl ester (CAS 365542-21-8)
- 6-Benzyl-4-hydroxy-5,6,7,8-tetrahydro-1,6-naphthyridin-2(1H)-one (CAS 70336-89-9)
Recommended Standards
- 3-(2-(Benzyloxy)phenyl)oxetan-3-ol (CAS 1123787-70-1)
- (7-Ethyl-5-methoxyimidazo[1,2-a]quinolin-2-yl)methanol (CAS 114095-06-6)
- tert-butyl (2R,4R)-4-azido-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 1123305-97-4)
- 3-(4-Methoxyphenyl)-3-phenylpropanoic acid (CAS 114327-14-9)
- n-(3-Cyanobenzyl)tetrahydro-2h-pyran-4-carboxamide (CAS 1271663-97-8)
- tert-Butyl 4-(7-bromo-6,8-dichloroquinazolin-4-yl)piperazine-1-carboxylate (CAS 1698027-58-5)
- (1R,2R)-2-(3-Methoxyphenyl)cyclopropanecarboxylic Acid (CAS 110901-90-1)
- 4-Fluoro-2-formylbenzoic acid (CAS 1186047-15-3)
- 5-(4-Bromophenyl)-2-(cyclopentylthio)-1-(furan-2-ylmethyl)-1H-imidazole (CAS 1207010-11-4)
- tert-Butyl 4-[(morpholine-4-carbonyl)amino]piperidine-1-carboxylate (CAS 1233954-82-9)
- 5,6-Dichloro-N-isopropyl-1H-benzo[d]imidazol-2-amine (CAS 176161-55-0)
- 7-Methoxy-3-(methoxymethoxy)-8-((triisopropylsilyl)ethynyl)naphthalen-1-yl trifluoromethanesulfonate (CAS 2773311-56-9)
- Ethyl 3-chloro-4,4,4-trifluorobutyrate (CAS 1309602-63-8)
- Uremic Pentapeptide (CAS 71494-20-7)
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