1-(2,4-difluorophenyl)guanidine hydrochloride CAS 112677-40-4
| CAS No. | 112677-40-4 |
| Molecular Formula | C7H7F2N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.61 g/mol gives 1-(2,4-difluorophenyl)guanidine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2,4-difluorophenyl)guanidine hydrochloride (CAS 112677-40-4), molecular formula C7H7F2N3HCl and molecular weight 207.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,4-difluorophenyl)guanidine hydrochloride (C7H7F2N3HCl) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2,4-difluorophenyl)guanidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7F2N3 HCl |
| Molecular Weight | 207.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related difluorophenyl Standards
- 1-(1-(2,6-Difluorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl)ethanone (CAS 1000572-09-7)
- (2,4-Difluorophenyl)methanesulfonamide (CAS 1001026-56-7)
- Methyl 2-(2,3-difluorophenyl)-2-hydroxyacetate (CAS 1001159-03-0)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- (4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile (CAS 1002728-74-6)
- N-(2,5-Difluorophenyl)-3-methylbenzamide (CAS 1002813-62-8)
- 4-(3,5-Difluorophenyl)piperidinehydrochloride (CAS 1004618-89-6)
- 4-(2,3-difluorophenyl)piperidine hydrochloride (CAS 1004618-90-9)
Recommended Standards
- 2,4-Diamino-6-ethylpyrimidin-5-ol (CAS 83403-29-6)
- (E)-4-(2-Carboxyvinyl)benzoic acid (CAS 56148-65-3)
- 2-(4-(Benzyloxy)-3-methoxyphenyl)acetaldehyde (CAS 16209-52-2)
- 2-Bromo-6-(bromomethyl)-4-(trifluoromethyl)pyridine (CAS 1807015-52-6)
- NG,NG’-Dimethyl-L-arginine-d6 (CAS 1331888-08-4)
- 2-Bromo-4-fluoro-1-(2-nitrovinyl)benzene (CAS 1173360-91-2)
- 1-(2-(Thiophen-3-yl)ethyl)cyclobutan-1-amine (CAS 1495575-94-4)
- 2-Chloro-4-(fluorosulfonyl)phenyl methanesulfonate (CAS 23383-87-1)
- (S)-tert-Butyl (1-(2-aminoethyl)pyrrolidin-3-yl)(ethyl)carbamate (CAS 1354015-89-6)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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