1,2,3,4-Tetrahydrobenzo[b]azepin-5-one CAS 1127-74-8
| CAS No. | 1127-74-8 |
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1,2,3,4-Tetrahydrobenzo[b]azepin-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1,2,3,4-Tetrahydrobenzo[b]azepin-5-one (CAS 1127-74-8) is a high-purity analytical reference standard with the molecular formula C10H11NO and a molecular weight of 161.20 g/mol.
Structurally, 1,2,3,4-Tetrahydrobenzo[b]azepin-5-one (C10H11NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 161.20 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Tetrahydrobenzo Standards
- 1,3,5,7-Tetrahydrobenzo[1,2-c:4,5-c']difuran (CAS 120512-90-5)
- 1,2,3,4-tetrahydrobenzo(e)(1,4)diazepin-5-one (CAS 28544-83-4)
- 2,3,5,6-Tetrahydrobenzo[1,2-b:5,4-b']difuran (CAS 57052-75-2)
- 1,4,5,8-Tetrahydrobenzo[1,2-d:4,5-d']diimidazole (CAS 172600-83-8)
- 6-Methyl-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepine (CAS 1278416-43-5)
- (R)-2,3,4,5-tetrahydrobenzo[b]oxepin-5-amine (CAS 1567915-72-3)
- 7-Methyl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepine (CAS 51585-35-4)
- 4,5,6,7-Tetrahydrobenzo[b]thiophene-2-carbonitrile (CAS 57021-54-2)
Recommended Standards
- 2,5,7-trimethylpyrazolo[1,5-a]pyrimidine (CAS 112581-74-5)
- 4-Cyclopropylbenzamide (CAS 1129-08-4)
- N,N-Dimethylimidazo[1,2-a]pyridin-3-amine (CAS 112357-05-8)
- 3-(3-Methoxyphenyl)propanenitrile (CAS 1129-59-5)
- Benzyl (2-(benzylamino)-2-oxo-1-phenylethyl)carbamate (CAS 1379796-36-7)
- 5-Amino-3-(3-tetrahydrofuryl)isoxazole (CAS 1218915-66-2)
- 2-Benzoyl-N-(4-methoxyphenyl)hydrazine-1-carbothioamide (CAS 38240-77-6)
- Levocetirizine Dihydrochloride (CAS 130018-87-0)
- 3-((4-Ethoxyphenyl)carbamoyl)-1,2,2-trimethylcyclopentane-1-carboxylic acid (CAS 7153-49-3)
- 5-chloro-2-fluoro-4-nitrobenzene-1-sulfonyl chloride (CAS 1803605-95-9)
- tert-Butyl 4-((tetrahydro-2H-pyran-4-yl)amino)piperidine-1-carboxylate (CAS 710977-70-1)
- 2-Methyl-4,6-diphenylpyrimidine (CAS 22114-38-1)
- 3-Bromo-5-(bromomethyl)benzoic acid (CAS 1261758-98-8)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com