2,4-Dichloro-5,6,7,8-tetrahydroquinazoline CAS 1127-85-1
| CAS No. | 1127-85-1 |
| Molecular Formula | C8H8Cl2N2 |
| Molecular Weight | 203.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 203.07 g/mol gives 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,4-Dichloro-5,6,7,8-tetrahydroquinazoline (CAS 1127-85-1), molecular formula C8H8Cl2N2 and molecular weight 203.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2N2 |
| Molecular Weight | 203.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate (CAS 158407-04-6)
- (S)-2-amino-N-(3-methoxypropyl)-4-methylpentanamide (CAS 742694-73-1)
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