Ethyl 2-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate CAS 112733-45-6

Purity 97%+In StockPharmaceutical Standards
CAS No.112733-45-6
Molecular FormulaC12H11ClN2O4
Molecular Weight282.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 2-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate CAS 112733-45-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies Ethyl 2-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate (CAS 112733-45-6), a certified reference material (molecular formula C12H11ClN2O4, MW 282.68 g/mol) for analytical method development and quality control.

Structurally, Ethyl 2-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate (C12H11ClN2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 282.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO manufactures Ethyl 2-(7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H11ClN2O4
Molecular Weight282.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms2

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