Ropivacaine EP Impurity G HCI CAS 112773-90-7
| CAS No. | 112773-90-7 |
| Molecular Formula | C17H26N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ropivacaine EP Impurity G HCI (CAS 112773-90-7, C17H26N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ropivacaine EP Impurity G HCI is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 310.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H26N2O HCl |
| Molecular Weight | 310.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ropivacaine Standards
- Ropivacaine EP Impurity E(R-Isomer) (CAS 1050482-18-2)
- Ropivacaine-d7 Hydrochloride (CAS 1217667-10-1)
- Ropivacaine Hydrochloride Monohydrate (CAS 132112-35-7)
- Ropivacaine Impurity 9 (CAS 13388-86-8)
- Ropivacaine Impurity 16 (CAS 1391053-59-0)
- Ropivacaine Impurity 37 (CAS 1583238-33-8)
- Ropivacaine Impurity 34 (CAS 175888-75-2)
- Ropivacaine Impurity 19 (CAS 1817657-89-8)
Recommended Standards
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- 1, 2, 3, 3a, 4, 8b- Hexahydrocyclopent[b] indole (CAS 80278-94-0)
- 6-Methoxybenzo[d]isoxazole-3-carboxylic acid (CAS 28691-48-7)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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