4-(Methylthio)benzene-1-sulfonyl chloride, 97% CAS 1129-25-5
| CAS No. | 1129-25-5 |
| Molecular Formula | C7H7ClO2S2 |
| Molecular Weight | 222.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Methylthio)benzene-1-sulfonyl chloride, 97% (CAS 1129-25-5), a certified reference material (molecular formula C7H7ClO2S2, MW 222.71 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-(Methylthio)benzene-1-sulfonyl chloride, 97% is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO2S2 |
| Molecular Weight | 222.71 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
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- 1-(4-(Methylthio)phenyl)hexan-1-one (CAS 101267-05-4)
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- trans-2-(4-(Methylthio)phenyl)cyclohexanol (CAS 933674-58-9)
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Recommended Standards
- 2-Chloro-4-(pentan-3-ylamino)benzonitrile (CAS 1097794-79-0)
- 4-Chloro-2-(pentylamino)benzonitrile (CAS 1156962-93-4)
- 2-Chloro-4-(pentylamino)benzonitrile (CAS 1094493-65-8)
- 4-Cyclohexylbenzoyl chloride (CAS 121193-16-6)
- Methyl (2S,4S)-4-(2-methoxy-4-methylphenoxy)-2-pyrrolidinecarboxylate (CAS 1217707-44-2)
- Isocorydine N-Oxide (CAS 25405-80-5)
- 4-((3-(1H-imidazol-1-yl)propyl)amino)-3-nitro-2H-chromen-2-one (CAS 294853-70-6)
- 1-(Benzyloxy)-3-methyl-5-nitrobenzene (CAS 1881291-17-3)
- Acitretin Impurity 4 (CAS 20469-61-8)
- Methyl 8-methoxyindolizine-7-carboxylate (CAS 1706460-04-9)
- 4,4'-Bicyclohexanone (CAS 23391-99-3)
- Cobalt(II) Sulfamate Hydrate (CAS 14017-41-5)
- 4-Methoxy-2,3-dimethyliodobenzene (CAS 17938-70-4)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com