Sapropterin Impurity 1 CAS 1131-35-7
| CAS No. | 1131-35-7 |
| Molecular Formula | C6H7N5O2 |
| Molecular Weight | 181.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sapropterin Impurity 1 (C6H7N5O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Sapropterin Impurity 1 (CAS 1131-35-7, C6H7N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sapropterin Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7N5O2 |
| Molecular Weight | 181.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 5 |
Related Sapropterin Standards
- Sapropterin Impurity 2 (CAS CATO-C4X-27662)
- Sapropterin Impurity 5 (CAS 17838-80-1)
- Sapropterin Impurity 4 (CAS CATO-C4X-27664)
- Sapropterin (CAS 62989-33-7)
- Sapropterin Impurity 7 (CAS 6228-40-6)
- Sapropterin Impurity 3 (CAS CATO-C4X-27663)
- Sapropterin D3 (CAS CATO-C4X-31026)
- Sapropterin impurity 3 (CAS CATO-C4X-31023)
Recommended Standards
- Tolvaptan Impurity 17 (CAS 1975-51-5)
- L-Glucose-1-13C (CAS 478519-02-7)
- Dopamine Impurity 3 (CAS 89942-72-3)
- 4-Nitrophenyl Acetate (CAS 830-03-5)
- Indobufen Impurity 15 (CAS 160723-33-1)
- Cefaclor Impurity 70 (CAS CATO-C4X-127070)
- Atracurium Impurity 106 (CAS CATO-C4X-1850106)
- 3-(3-chloropropyl)-1-methyl-1H-pyrazole-4-carbaldehyde (CAS 2060047-27-8)
- Neurokinin B (CAS 86933-75-7)
- Linagliptin Impurity 89 (CAS CATO-C4X-110189)
- Tripropylene Glycol (mixture of isomers) (CAS 24800-44-0)
- 2-Chloro-5,6,7,8-tetrahydro-1,7-naphthyridine hydrochloride (CAS 1401034-59-0)
- Tert-butyl 3-(thietan-3-ylamino)-8-azabicyclo[3.2.1]Octane-8-carboxylate (CAS 2006946-47-8)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com