3,4-Dihydroisoquinoline-2(1H)-carboximidamide hydrochloride CAS 1131-66-4
| CAS No. | 1131-66-4 |
| Molecular Formula | C10H13N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,4-Dihydroisoquinoline-2(1H)-carboximidamide hydrochloride (CAS 1131-66-4), molecular formula C10H13N3HCl and molecular weight 211.69 g/mol, is a CATO reference standard with documented purity and traceability.
3,4-Dihydroisoquinoline-2(1H)-carboximidamide hydrochloride (C10H13N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,4-Dihydroisoquinoline-2(1H)-carboximidamide hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13N3 HCl |
| Molecular Weight | 211.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dihydroisoquinoline Standards
- 5-Methyl-3,4-dihydroisoquinoline (CAS 100643-54-7)
- 7-Methyl-3,4-dihydroisoquinoline (CAS 102652-86-8)
- 1-Oxo-1,2-dihydroisoquinoline-4-carbohydrazide (CAS 103262-50-6)
- 1,1'-(3,4-Dihydroisoquinoline-2,5(1H)-diyl)diethanone (CAS 108825-20-3)
- 1-Oxo-1,2-dihydroisoquinoline-6-carbaldehyde (CAS 1150618-26-0)
- 3-oxo-2,3-dihydroisoquinoline-8-carbonitrile (CAS 1175272-54-4)
- 1-Oxo-1,2-dihydroisoquinoline-7-carbonitrile (CAS 1184913-64-1)
- 1-Oxo-1,2-dihydroisoquinoline-5-carbaldehyde (CAS 1184913-66-3)
Recommended Standards
- 1-(3-(Tert-butyl)phenyl)ethan-1-amine (CAS 155734-78-4)
- (3S)-3-iodopyrrolidine;hydrochloride (CAS 1354011-67-8)
- rac-(4aα)-4a,5,9,10,11,12-Hexahydro-1,5-dibromo-11-formyl-3-methoxy-6H-benzofuro[3a,3,2-e,f][2]benzazepin-6-one (CAS 1076198-20-3)
- 2-(2-Chlorophenyl)-1-(4-iodophenyl)ethan-1-one (CAS 187617-06-7)
- Methyl 2-amino-3-(2,4-dimethoxyphenyl)propanoate (CAS 174906-29-7)
- 1-(2-(5-Methylthiophen-2-yl)-2-oxoethyl)-1h-1,2,4-triazole-3-carbonitrile (CAS 1210847-82-7)
- Trans-N1,N4-dimethylcyclohexane-1,4-diamine (CAS 6921-01-3)
- (E)-3-(3-methoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 52182-14-6)
- Diphenyleneiodonium Chloride (CAS 4673-26-1)
- Exenatide (CAS 141758-74-9)
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