Ethyl 2-(2,4-difluoro-5-iodobenzoyl)-3-(dimethylamino)acrylate CAS 1131640-51-1
| CAS No. | 1131640-51-1 |
| Molecular Formula | C14H14F2INO3 |
| Molecular Weight | 409.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 2-(2,4-difluoro-5-iodobenzoyl)-3-(dimethylamino)acrylate (CAS 1131640-51-1), a certified reference material (molecular formula C14H14F2INO3, MW 409.17 g/mol) for analytical method development and quality control.
Ethyl 2-(2,4-difluoro-5-iodobenzoyl)-3-(dimethylamino)acrylate (C14H14F2INO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Ethyl 2-(2,4-difluoro-5-iodobenzoyl)-3-(dimethylamino)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14F2INO3 |
| Molecular Weight | 409.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 697762-39-3 Ethyl 2-(2,4-difluoro-5-iodobenzoyl)-3-(dimethylamino)prop-2-enoate DTXSID90699588 (CAS 697762-39-3)
- 6,8-Difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester (CAS 158585-86-5)
- 3-[1-[Difluoro[(trifluoroethenyl)oxy]methyl]-1,2,2,2-tetrafluoroethoxy]-2,2,3,3-tertrafluoropropanoic acid (CAS 69087-46-3)
- Methyl 5,8-difluoro-4-(piperazin-1-yl-N-BOC protected)quinoline-2-carboxylate (CAS 887267-66-5)
- 3-[1-[Difluoro[(Trifluoroethenyl)Oxy]Methyl]-1,2,2,2-Tetrafluoroethoxy]-2,2,3,3-Tetrafluoropropanamide (CAS 69804-18-8)
- 1-Benzyl-6,7-difluoro-3-(phenylsulfonyl)quinolin-4(1H)-one (CAS 899213-86-6)
- 2,6-Difluoro-N-{4-[4-(4-fluorophenyl)piperazin-1-yl]phenyl}benzamide (CAS 303151-22-6)
- 4-(2,3-Difluoro-4-propoxyphenyl)-4'-pentyl-1,1'-bi(cyclohexane) (CAS 2196179-78-7)
Recommended Standards
- Methyl (2Z)-3-[(4-chloro-2-fluorophenyl)amino]-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]prop-2-enoate (CAS 478033-79-3)
- 2,7-Dibromo-9-hexyl-9H-carbazole (CAS 654676-12-7)
- 2-(2,4-Dichlorophenoxy)-N'-(5-nitro-2-oxoindolin-3-ylidene)acetohydrazide (CAS 325777-37-5)
- 3,6-Dibromo-9-hexyl-9H-carbazole (CAS 150623-72-6)
- 3-Acetylthianaphthene, 98% (CAS 26168-40-1)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-((4-chlorobenzyl)amino)acetamide (CAS 297150-43-7)
- 51860-92-5 CTK1E4849 Pentanoic acid, 2-propyl-, butyl ester (CAS 51860-92-5)
- 1-(5-Amino-3-indolyl)ethanone (CAS 634182-56-2)
- 3-Acetyl-5-formylbenzonitrile (CAS 1393567-18-4)
- Naphthalene-2,6-diyldimethanamine (CAS 46305-65-1)
- 6-Iodobenzo[d]thiazole-2-carbonitrile (CAS 1823057-00-6)
- Methyl 4-(((trifluoromethyl)sulfonyl)oxy)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate (CAS 1359705-35-3)
- 1-Methyl-n-(2-methylphenyl)piperidin-4-amine (CAS 1020964-10-6)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com