Trifluoro-methanesulfonic acid (chloromethyl)methyl-2-propen-1-ylsilyl ester CAS 1132657-38-5
| CAS No. | 1132657-38-5 |
| Molecular Formula | C6H10ClF3O3SSi |
| Molecular Weight | 282.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Trifluoro-methanesulfonic acid (chloromethyl)methyl-2-propen-1-ylsilyl ester.
Trifluoro-methanesulfonic acid (chloromethyl)methyl-2-propen-1-ylsilyl ester (CAS 1132657-38-5) is a high-purity analytical reference standard with the molecular formula C6H10ClF3O3SSi and a molecular weight of 282.74 g/mol.
The molecular framework of Trifluoro-methanesulfonic acid (chloromethyl)methyl-2-propen-1-ylsilyl ester (C6H10ClF3O3SSi) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Trifluoro-methanesulfonic acid (chloromethyl)methyl-2-propen-1-ylsilyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10ClF3O3SSi |
| Molecular Weight | 282.74 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Trifluoro Standards
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- ethyl 3,3,3-trifluoro-2-hydroxy-2-[(2,2,2-trifluoroacetyl)amino]propanoate (CAS 329182-36-7)
- (3E)-1,1,1-Trifluoro-4-{[4-(trifluoromethyl)phenyl]amino}but-3-en-2-one (CAS 478040-72-1)
- (R)-2,2,2-trifluoro-1-(3'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-ol (CAS 1116459-85-8)
- (3E)-1,1,1-Trifluoro-4-{[2-(1H-indol-3-yl)ethyl]amino}but-3-en-2-one (CAS 478040-78-7)
- 2,2,2-Trifluoro-N-(3-fluoro-4-methoxy-2-(methylthio)phenyl)acetamide (CAS 2586125-97-3)
- 1,1,1-Trifluoro-2-(4-methylpyridin-2-yl)propan-2-yl methanesulfonate (CAS 1396893-44-9)
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Recommended Standards
- 2'-Methoxy-[1,1'-biphenyl]-3-sulfonyl chloride (CAS 1032506-66-3)
- 2-Chloro-5-(3-methylsulfonylphenyl)phenol (CAS 1261921-84-9)
- 4-(m-Tolyloxy)benzenesulfonyl chloride (CAS 1016513-15-7)
- 3-Chloro-4'-(methylsulfonyl)-[1,1'-biphenyl]-4-ol (CAS 1261991-24-5)
- 4-(Bromomethyl)-3-methylpyridine (CAS 1227585-55-8)
- Droxinavir hydrochloride, >98% (HPLC) (CAS 155662-50-3)
- n-Butyl-2-chloropropanamide (CAS 94318-73-7)
- 2-Chloro-3-(5-chloro-2-methoxyphenyl)-1-propene (CAS 951895-02-6)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(pyridin-2-ylmethyl)-1H-pyrrole-2-carboxamide (CAS 338397-53-8)
- 1,1'-(Hydrazine-1,2-diylidenebis(methanylylidene))bis(naphthalen-2-ol) (CAS 2387-03-3)
- (E)-3-(3,5-Dimethylphenyl)prop-2-en-1-ol (CAS 388631-81-0)
- 3-Phenylbenzyl isothiocyanate (CAS 1001569-47-6)
- N3-Ph-NHS ester (CAS 53053-08-0)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
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