Methyl 8-bromo-4-chloro-5-fluoroquinoline-2-carboxylate CAS 1133115-52-2
| CAS No. | 1133115-52-2 |
| Molecular Formula | C11H6BrClFNO2 |
| Molecular Weight | 318.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 318.53 g/mol gives Methyl 8-bromo-4-chloro-5-fluoroquinoline-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 8-bromo-4-chloro-5-fluoroquinoline-2-carboxylate (CAS 1133115-52-2), a certified reference material (molecular formula C11H6BrClFNO2, MW 318.53 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, Methyl 8-bromo-4-chloro-5-fluoroquinoline-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6BrClFNO2 |
| Molecular Weight | 318.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
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