2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile CAS 1133123-06-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile.

CATO supplies 2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile (CAS 1133123-06-4), a certified reference material (molecular formula C12H7F3N2O, MW 252.19 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 252.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-Oxo-7-(trifluoromethyl)quinolin-1(4H)-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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