1-Ethyl-6-methoxy-5-nitro-1H-indazol-3-amine CAS 1133430-76-8
| CAS No. | 1133430-76-8 |
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Ethyl-6-methoxy-5-nitro-1H-indazol-3-amine (CAS 1133430-76-8), molecular formula C10H12N4O3 and molecular weight 236.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Ethyl-6-methoxy-5-nitro-1H-indazol-3-amine (C10H12N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Ethyl-6-methoxy-5-nitro-1H-indazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- 4-(6-Methoxy[1,2,4]triazolo[4,3-b]pyridazin-3-yl)butanoic acid (CAS 1322605-17-3)
- 7-Methoxy-2-(methoxymethyl)pyrazolo[1,5-a]pyridine-4-carboxylic acid (CAS 1009602-42-9)
- 4-Methoxy-3-(2-oxoimidazolidin-1-yl)benzoic acid (CAS 1354954-25-8)
- n-Methoxy-n-methyl-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-7-carboxamide (CAS 1394041-17-8)
- (2E)-3-(8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)acrylic acid (CAS 852389-16-3)
- 1-(4-Methoxy-7-nitroindolin-1-yl)ethan-1-one (CAS 295325-60-9)
- 1-(5-Methoxy-6-nitroindolin-1-yl)ethanone (CAS 23772-37-4)
- 5-Methoxy-3-(2-methoxy-5-methylphenyl)-1,3,4-oxadiazol-2(3H)-one (CAS 98414-86-9)
Recommended Standards
- Imatinib Impurity 48 (CAS 1131605-15-6)
- 4-(2,2,2-Trifluoroethyl)biphenyl (CAS 1204295-81-7)
- 3,6-Di(pyridin-3-yl)-1,2,4,5-tetrazine (CAS 107599-30-4)
- Methyl 2-(methoxymethyl)-7-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1211484-10-4)
- 2-((5-(2-Bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide (CAS 332388-13-3)
- N-(7-iodo-4-methoxythiazolo[4,5-c]pyridin-2-yl)benzamide (CAS 2273883-69-3)
- 2-(2-Phenyl-2h-1,2,3-triazol-4-yl)ethan-1-amine hydrochloride (CAS 1172491-02-9)
- Sulfatinib (CAS 1308672-74-3)
- 2-Amino-3-(3-ethoxy-2-hydroxyphenyl)propanoic acid (CAS 1343260-68-3)
- 2-Amino-1-(3-((benzyl(isopropyl)amino)methyl)pyrrolidin-1-yl)ethanone (CAS 1353972-97-0)
- 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 1427379-12-1)
- 3-Sulfamoylpropionic Acid (CAS 15441-10-8)
- 3-Picolyl isothiocyanate hydrobromide (CAS 147342-57-2)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com