(R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride CAS 1134603-02-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride.

(R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride (CAS 1134603-02-3) is a high-purity analytical reference standard with the molecular formula C11H22N2HCl and a molecular weight of 218.77 g/mol.

The molecular framework of (R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride (C11H22N2HCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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