Pimavanserin Impurity 20 CAS 1134815-71-6
| CAS No. | 1134815-71-6 |
| Molecular Formula | C25H34FN3O3 |
| Molecular Weight | 443.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pimavanserin Impurity 20.
As a process- or degradation-related impurity, Pimavanserin Impurity 20 (CAS 1134815-71-6, C25H34FN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pimavanserin Impurity 20 (C25H34FN3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Pimavanserin Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H34FN3O3 |
| Molecular Weight | 443.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Pimavanserin Standards
- Pimavanserin Impurity 11 (CAS CATO-C4X-193811)
- Pimavanserin-d4 (CAS 706779-91-1 (unlabelled))
- Pimavanserin (CAS 706779-91-1)
- Pimavanserin Impurity 32 (CAS CATO-C4X-193832)
- Pimavanserin Impurity 68 (CAS CATO-C4X-193868)
- Pimavanserin Impurity 10 (CAS CATO-C4X-193810)
- Pimavanserin Impurity 13 (CAS 639863-77-7)
- Pimavanserin impurity 55 (CAS CATO-C4X-193855)
Recommended Standards
- SKLB-1028 (CAS 1350544-93-2)
- Pigment Red 81 (CAS 12224-98-5)
- Pazopanib-d6 (CAS 1219592-01-4)
- Pigment Violet 1 (CAS 1326-03-0)
- Progesterone EP Impurity A (CAS 24377-08-0)
- Edoxaban Impurity 51 (CAS CATO-C4X-106351)
- Folic Acid EP Impurity H (CAS 2366274-27-1)
- 1-(3-Nitro-4-pyrrolidin-1-ylphenyl)ethanone (CAS 887595-31-5)
- N,N'-Bis-(3-fluoro-benzyl)-cyclohexane-1,4-diamine (CAS 1250898-95-3)
- 3-(Morpholinomethyl)bicyclo[1.1.1]Pentan-1-amine (CAS 2303047-83-6)
- N1-[(1E)-(4-Methylphenyl)methylene]-4-phenyl-1H-imidazole-1,2-diamine (CAS 1993648-80-8)
- 9-bromofluorene (CAS 1940-57-4)
- Dihydrosafrole (CAS 94-58-6)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com