4-([1,1-Biphenyl]-4-yloxy)-3-chlorophenylamine-hydrochloride CAS 1135066-56-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1135066-56-6
Molecular FormulaC18H14ClNO
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-([1,1-Biphenyl]-4-yloxy)-3-chlorophenylamine-hydrochloride CAS 1135066-56-6 chemical structure

Description

The occurrence of 4-([1,1-Biphenyl]-4-yloxy)-3-chlorophenylamine-hydrochloride is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-([1,1-Biphenyl]-4-yloxy)-3-chlorophenylamine-hydrochloride (CAS 1135066-56-6) is a high-purity analytical reference standard with the molecular formula C18H14ClNOHCl and a molecular weight of 332.22 g/mol.

4-([1,1-Biphenyl]-4-yloxy)-3-chlorophenylamine-hydrochloride (C18H14ClNOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H14ClNO HCl
Molecular Weight332.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms1

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