6-Bromo-3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one CAS 1135283-30-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1135283-30-5
Molecular FormulaC10H6BrF3N2O
Molecular Weight307.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one CAS 1135283-30-5 chemical structure

Description

Structurally, 6-Bromo-3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one (C10H6BrF3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 307.07 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

6-Bromo-3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one (CAS 1135283-30-5), molecular formula C10H6BrF3N2O and molecular weight 307.07 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H6BrF3N2O
Molecular Weight307.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Br-containing
Nitrogen Atoms2

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