Methyl 2-(6-chloro-8-iodoimidazo[1,2-a]pyridin-2-yl)acetate CAS 1135283-37-2

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Methyl 2-(6-chloro-8-iodoimidazo[1,2-a]pyridin-2-yl)acetate (CAS 1135283-37-2), molecular formula C10H8ClIN2O2 and molecular weight 350.54 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl 2-(6-chloro-8-iodoimidazo[1,2-a]pyridin-2-yl)acetate (C10H8ClIN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), Methyl 2-(6-chloro-8-iodoimidazo[1,2-a]pyridin-2-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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