5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile CAS 1135283-49-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1135283-49-6
Molecular FormulaC8H3BrClF3N2
Molecular Weight299.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile CAS 1135283-49-6 chemical structure

Description

The occurrence of 5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile (CAS 1135283-49-6), a certified reference material (molecular formula C8H3BrClF3N2, MW 299.48 g/mol) for analytical method development and quality control.

Based on its molecular formula C8H3BrClF3N2, 5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 299.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H3BrClF3N2
Molecular Weight299.48 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms2

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