Gliclazide EP Impurity D CAS 1136426-19-1
| CAS No. | 1136426-19-1 |
| Molecular Formula | C15H20N2O3S |
| Molecular Weight | 308.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Gliclazide EP Impurity D (C15H20N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Gliclazide EP Impurity D (CAS 1136426-19-1) is a certified pharmaceutical impurity reference standard with the molecular formula C15H20N2O3S and a molecular weight of 308.40 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O3S |
| Molecular Weight | 308.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Gliclazide Standards
- Gliclazide EP Impurity E (CAS 1808087-53-7)
- Gliclazide EP Impurity G (CAS CATO-C4X-14497)
- Gliclazide EP Impurity F (CAS 1076198-18-9)
- Gliclazide (CAS 21187-98-4)
- Gliclazide-d4 (CAS 1185039-30-8)
- Gliclazide Impurity 16 (CAS CATO-C4X-144916)
- Gliclazide-d4 (CAS 185039-30-8)
- Gliclazide Impurity 1 (Carboxy Gliclazide) (CAS 38173-52-3)
Recommended Standards
- N-methyl-6-((phenylthio)methyl)-2-(pyridin-4-yl)pyrimidin-4-amine (CAS 303147-63-9)
- Ertapenem Impurity 61 (CAS CATO-C4X-163361)
- N-allyl-1-(phenylsulfonyl)piperidine-4-carboxamide (CAS 444112-78-1)
- Benzylpenicillin Impurity 48 (CAS CATO-C4X-189948)
- Pimecrolimus Impurity 12 (CAS CATO-C4X-173112)
- Fluconazole Impurity 37 (CAS CATO-C4X-101937)
- Nafamostat impurity 111 (CAS CATO-C4X-1332111)
- 1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene (CAS 916421-00-6)
- 1,1'-[(1S)-4,4'-Bis(trimethylsilyl)[1,1'-binaphthalene]-2,2'-diyl]bis[1,1-diphenylphosphine] (CAS 933996-97-5)
- 5,7-Difluoro-2,3-dihydro-1H-inden-1-one (CAS 84315-25-3)
- N-{[3-(4-methoxyphenyl)isoxazol-5-yl]methyl}-N-methylamine hydrochloride (CAS 1170166-70-7)
- (3-chloro-1,2,4-triazin-5-yl)methanol (CAS 1784629-98-6)
- 3-Chloro-2-(difluoromethyl)benzonitrile (CAS 1261776-59-3)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com