5-((6-Chloropyrimidin-4-yl)amino)pyrazine-2-carbonitrile CAS 1137475-05-8
| CAS No. | 1137475-05-8 |
| Molecular Formula | C9H5ClN6 |
| Molecular Weight | 232.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-((6-Chloropyrimidin-4-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-05-8) is a high-purity analytical reference standard with the molecular formula C9H5ClN6 and a molecular weight of 232.63 g/mol.
5-((6-Chloropyrimidin-4-yl)amino)pyrazine-2-carbonitrile (C9H5ClN6) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN6 |
| Molecular Weight | 232.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Chloropyrimidin Standards
- 2-(5-Chloropyrimidin-2-yl)-1-phenylethanone (CAS 112336-12-6)
- 1-(6-Chloropyrimidin-4-yl)indoline (CAS 293292-33-8)
- 2-(2-Chloropyrimidin-4-yl)-2,3-dihydro-1h-isoindole (CAS 488817-09-0)
- 2-(6-Chloropyrimidin-4-yl)isoindoline (CAS 945896-75-3)
- 2-((4-Chloropyrimidin-2-yl)oxy)benzonitrile (CAS 1159826-56-8)
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- 3-(2-Chloropyrimidin-4-yl)pyrazolo[1,5-b]pyridazine (CAS 2244975-98-0)
- 4-(2-Chloropyrimidin-4-yl)-N,N-dimethylaniline (CAS 936939-36-5)
Recommended Standards
- 4-Chloro-1,8-naphthalic anhydride (CAS 4053-08-1)
- 3-(chloromethyl)-6-(2,2,2-trifluoroethoxy)pyridazine (CAS 1250327-94-6)
- Methyl 2-chloro-5,6-dimethoxypyrimidine-4-carboxylate (CAS 923938-13-0)
- 4-Chloro-1-(pyrazin-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1522996-42-4)
- Ethyl 4-cyano-3-hydroxy-5-methylsulfanylthiophene-2-carboxylate (CAS 203189-41-7)
- [4-Amino-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]methanol (CAS 1416373-56-2)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-(4-methoxyphenyl)cyclohexane-1,3-dione (CAS 439110-56-2)
- n-Allyl-5-(methylthio)-2-nitrobenzamide (CAS 1090684-40-4)
- (2S,4S)-4-Hydroxy-5-oxotetrahydrofuran-2-carboxylic acid (CAS 120742-25-8)
- Pyridazin-3-yl(pyridin-3-yl)methanone (CAS 188630-95-7)
- 3-Bromo-4-cyclopropoxybenzoic acid (CAS 1243470-34-9)
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- 3-(4-Chloro-2-ethylphenoxy)piperidinehydrochloride (CAS 1220018-98-3)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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