5-((5-Amino-4-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile CAS 1137475-66-1
| CAS No. | 1137475-66-1 |
| Molecular Formula | C18H22N8 |
| Molecular Weight | 350.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-((5-Amino-4-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile.
5-((5-Amino-4-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-66-1) is a high-purity analytical reference standard with the molecular formula C18H22N8 and a molecular weight of 350.42 g/mol.
The molecular framework of 5-((5-Amino-4-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile (C18H22N8) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-((5-Amino-4-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22N8 |
| Molecular Weight | 350.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 8 |
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Recommended Standards
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- 9,9-Bis(4-Hydroxyphenyl)Fluorene (CAS 3236-71-3)
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- Insulin aspart (CAS 116094-23-6)
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- (Z)-benzyl but-2-enoate (CAS 92758-75-3)
- 2,5-Bis(pentyloxy)terephthalaldehyde (CAS 278186-49-5)
- Pentaerythrityl tetrastearate (CAS 115-83-3)
- 1-(7-Methoxy-2H-pyrazolo[3,4-c]pyridin-2-yl)ethanone (CAS 76006-05-8)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
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