Methyl 4-(azepan-4-ylamino)-6-((5-cyanopyrazin-2-yl)amino)nicotinate CAS 1137476-98-2
| CAS No. | 1137476-98-2 |
| Molecular Formula | C18H21N7O2 |
| Molecular Weight | 367.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 4-(azepan-4-ylamino)-6-((5-cyanopyrazin-2-yl)amino)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Methyl 4-(azepan-4-ylamino)-6-((5-cyanopyrazin-2-yl)amino)nicotinate (CAS 1137476-98-2), a certified reference material (molecular formula C18H21N7O2, MW 367.41 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 4-(azepan-4-ylamino)-6-((5-cyanopyrazin-2-yl)amino)nicotinate (C18H21N7O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H21N7O2 |
| Molecular Weight | 367.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 7 |
Related Methyl Standards
- 5-(4-(Azepan-1-ylsulfonyl)phenyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 917561-72-9)
- 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(3-cyanophenyl)acetamide (CAS 1226441-77-5)
- 4-azepan-1-yl-1,1,1-trifluoro-3-(1-phenyl-1H-1,2,3,4-tetraazol-5-yl)but-3-en-2-one (CAS 152427-09-3)
- N-((4-(Azepan-1-ylsulfonyl)phenyl)carbamothioyl)propionamide (CAS 590400-06-9)
- 4-[4-(Azepan-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one (CAS 882000-10-4)
- N1-(2-(Azepan-1-yl)-2-(thiophen-3-yl)ethyl)-N2-cyclopentyloxalamide (CAS 946303-63-5)
- (2-(6-(Azepan-1-yl)pyridin-3-yl)piperidin-1-yl)(phenyl)methanone (CAS 1352536-31-2)
- (S)-1-(4-(azepan-1-ylsulfonyl)phenyl)-2-bromoethan-1-ol (CAS 1175852-29-5)
Recommended Standards
- Methyl 6-((5-cyanopyrazin-2-yl)amino)-4-((piperidin-2-ylmethyl)amino)nicotinate (CAS 1137476-95-9)
- (1-benzyl-4,4-difluoro-pyrrolidin-3-yl) 4-methylbenzenesulfonate (CAS 1799916-94-1)
- Methyl 6-((5-cyanopyrazin-2-yl)amino)-4-((1-methylpiperidin-4-yl)amino)nicotinate (CAS 1137475-97-8)
- Methyl 4-(((tert-butoxycarbonyl)amino)methyl)-6-fluoro-2,2-dimethylchroman-8-carboxylate (CAS 1956380-93-0)
- 160938-09-0 N-Methyl-2-morpholinoethanamine hydrochloride ST2407465 (CAS 160938-09-0)
- 1-Bromo-4-(2-methoxyethoxy)benzene (CAS 39255-23-7)
- 1-(1-Methyl-4-nitro-1H-pyrazol-5-yl)pyrrolidin-3-amine dihydrochloride (CAS 1363405-43-9)
- 1-(2,4-Dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-2,2,2-trifluoroethan-1-one (CAS 2387601-75-2)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 578754-93-5)
- 2-(2-Fluoro-5-methylphenoxy)acetonitrile (CAS 1343339-45-6)
- Ezetimibe Impurity 92 (CAS 2469633-86-9)
- 3-Bromo-4'-(tert-butyl)-1,1'-biphenyl (CAS 1443351-07-2)
- tert-Butyl (4-(chloromethyl)pyridin-2-yl)carbamate (CAS 672324-82-2)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com