(S,Z)-3-(1-Hydroxyethylidene)-5-methylpyrrolidine-2,4-dione CAS 113757-64-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S,Z)-3-(1-Hydroxyethylidene)-5-methylpyrrolidine-2,4-dione.

(S,Z)-3-(1-Hydroxyethylidene)-5-methylpyrrolidine-2,4-dione (CAS 113757-64-5) is a high-purity analytical reference standard with the molecular formula C7H9NO3 and a molecular weight of 155.15 g/mol.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, (S,Z)-3-(1-Hydroxyethylidene)-5-methylpyrrolidine-2,4-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 155.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (S,Z)-3-(1-Hydroxyethylidene)-5-methylpyrrolidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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