4-(Difluorophenylmethyl)-2-fluoro-1-(trifluoromethyl)benzene CAS 1138445-35-8
| CAS No. | 1138445-35-8 |
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Difluorophenylmethyl)-2-fluoro-1-(trifluoromethyl)benzene (CAS 1138445-35-8), a certified reference material (molecular formula C14H8F6, MW 290.20 g/mol) for analytical method development and quality control.
The molecular framework of 4-(Difluorophenylmethyl)-2-fluoro-1-(trifluoromethyl)benzene (C14H8F6) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Difluorophenylmethyl)-2-fluoro-1-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluorophenylmethyl Standards
- 1-(Difluorophenylmethyl)-2-fluoro-3-(trifluoromethyl)benzene (CAS 1138445-34-7)
- 1-(Difluorophenylmethyl)-3-fluoro-5-(trifluoromethyl)benzene (CAS 1138445-38-1)
- 1-(Difluorophenylmethyl)-2-(trifluoromethyl)benzene (CAS 1138445-39-2)
- 1-(Difluorophenylmethyl)-3,5-difluorobenzene (CAS 1138445-32-5)
- 2-(Difluorophenylmethyl)-1,4-difluorobenzene (CAS 1138445-33-6)
- 1-(Difluorophenylmethyl)-3,5-bis(trifluoromethyl)benzene (CAS 1138445-31-4)
- 1-(Difluorophenylmethyl)-2-fluorobenzene (CAS 1204295-58-8)
- 1-(Difluorophenylmethyl)-4-fluorobenzene (CAS 144918-44-5)
Recommended Standards
- 5-Acetamido-2-(trifluoroacetamido)benzoic acid (CAS 1098397-49-9)
- 7-Bromo-2,8-dimethylquinoline-3-carboxylic acid (CAS 1189106-92-0)
- Methyl 2-(3-methyl-6-oxo-4-(trifluoromethyl)isoxazolo[5,4-b]pyridin-7(6H)-yl)acetate (CAS 1018047-44-3)
- n-((1,2,3-Thiadiazol-4-yl)methyl)-1-(4-bromothiophen-2-yl)methanamine (CAS 1340465-94-2)
- 1-(2,2-Diethoxyethyl)-1h-indole (CAS 159884-46-5)
- 5-Hydroxy-7-methoxy-3-(4-methoxyphenyl)quinolin-4(1H)-one (CAS 190774-08-4)
- 5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1352239-77-0)
- 1-(Trifluoromethyl)cyclopropanamine (CAS 112738-68-8)
- 5-Amino-4-cyano-1-phenyl-1H-pyrazole-3-carboxylic acid (CAS 1076197-28-8)
- n-(5-Acetyl-4-methylthiazol-2-yl)-2-chloroacetamide (CAS 32519-70-3)
- 3-[(Boc-amino)methyl]-4-fluoroaniline (CAS 209899-48-9)
- 1H-Thieno[2',3':4,5]benzo[1,2-d]imidazole (CAS 356570-41-7)
- 2-(2-Chlorophenyl)-2-methyl-1-propanol (CAS 1176587-58-8)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
Why CATO?
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