4-Fluoro-2H-spiro[benzofuran-3,4'-piperidine] hydrochloride CAS 1138521-56-8
| CAS No. | 1138521-56-8 |
| Molecular Formula | C12H14FNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Fluoro-2H-spiro[benzofuran-3,4'-piperidine] hydrochloride (CAS 1138521-56-8) is a high-purity analytical reference standard with the molecular formula C12H14FNOHCl and a molecular weight of 243.71 g/mol.
The molecular framework of 4-Fluoro-2H-spiro[benzofuran-3,4'-piperidine] hydrochloride (C12H14FNOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14FNO HCl |
| Molecular Weight | 243.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
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- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
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- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- Tert-butyl 2-hydroxy-9-oxo-6-azaspiro[3.5]Nonane-6-carboxylate (CAS 2387598-90-3)
- Ethyl 3-(2,6-dimethylpiperidin-1-yl)propanoate (CAS 105836-42-8)
- 4-Hexadecanol (CAS 19781-43-2)
- Ethyl 6-oxopiperidine-2-carboxylate (CAS 127274-92-4)
- 2-(2,3-Dihydro-1h-inden-1-yl)ethan-1-ol (CAS 38425-66-0)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylpropanoic acid (CAS 1217722-24-1)
- n-(3-Ethynylphenyl)-1h-1,2,3-triazole-4-carboxamide (CAS 1428084-43-8)
- 3,5-Bis(methoxycarbonyl)benzoic acid (CAS 38588-64-6)
- 1-(2-(6-Mercapto-5-methylpyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352488-91-5)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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