9-(2-Chloroethyl)-9H-carbazole CAS 1140-35-8
| CAS No. | 1140-35-8 |
| Molecular Formula | C14H12ClN |
| Molecular Weight | 229.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 9-(2-Chloroethyl)-9H-carbazole.
9-(2-Chloroethyl)-9H-carbazole (CAS 1140-35-8) is a high-purity analytical reference standard with the molecular formula C14H12ClN and a molecular weight of 229.70 g/mol.
The molecular framework of 9-(2-Chloroethyl)-9H-carbazole (C14H12ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN |
| Molecular Weight | 229.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroethyl Standards
- 5-(1-Chloroethyl)-6-nitro-2H-1,3-benzodioxole (CAS 1308676-67-6)
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- 3-(2-Chloroethyl)-1,3-diazaspiro[4.5]decane-2,4-dione (CAS 53195-97-4)
- 6-(2-Chloroethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 86488-00-8)
- 9-(2-Chloroethyl)-6-(methylthio)-9H-purine (CAS 2846-81-3)
- 3-(2-Chloroethyl)-9-hydroxy-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 130049-77-3)
- N-(2-Chloroethyl)-2-methoxy-N-methylisonicotinamide (CAS 1820740-21-3)
- 1-(2-Chloroethyl)-3-(4-methoxyphenyl)urea (CAS 65536-40-5)
Recommended Standards
- 4-Chloro-2-(((1-hydroxy-2-methylpropan-2-yl)amino)methyl)phenol (CAS 1042627-07-5)
- Rabeprazole Impurity 35 (CAS 117977-20-5)
- 4-Chloro-2-(((1-hydroxybutan-2-yl)amino)methyl)phenol (CAS 1042623-95-9)
- 1-Cyclohexyl-5-oxopyrrolidine-3-carbonyl chloride (CAS 1181577-49-0)
- 5,6-Dimethyl-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1799-79-7)
- 2-(6-Bromo-3-pyridyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione (CAS 1816951-75-3)
- (R)-1-(4-fluoro-3-methylphenyl)-2-methylpropan-1-amine (CAS 1213687-45-6)
- (S)-tert-Butyl 3-((4-chloro-6-methylpyrimidin-2-yl)amino)pyrrolidine-1-carboxylate (CAS 1264033-77-3)
- 2,5-Bis(allyloxy)terephthalaldehyde (CAS 2377871-78-6)
- 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one (CAS 754239-64-0)
- 6,7-Dichloroquinoline-2-carbonitrile (CAS 1266845-77-5)
- N-(3-chloro-4-methylphenyl)-2-((5-(4-methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 335396-50-4)
- (E)-3,7,11-Trimethyldodeca-6,10-dien-1-ol (CAS 51411-24-6)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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