Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-5-carboxylate CAS 1140964-67-5
| CAS No. | 1140964-67-5 |
| Molecular Formula | C11H9ClN2O3 |
| Molecular Weight | 252.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-5-carboxylate (CAS 1140964-67-5), a certified reference material (molecular formula C11H9ClN2O3, MW 252.65 g/mol) for analytical method development and quality control.
Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-5-carboxylate (C11H9ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9ClN2O3 |
| Molecular Weight | 252.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 3-(Chloromethyl)-5-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,2,4-oxadiazole (CAS 1039860-69-9)
- 4-(Chloromethyl)-5-methyl-2-(2-nitrophenyl)oxazole (CAS 1048918-88-2)
- 4-(5-Chloromethyl-[1,2,4]oxadiazol-3-yl)-benzoic acid methyl ester (CAS 1092400-75-3)
- 4-(Chloromethyl)-5-methyl-2-(4-nitrophenyl)oxazole (CAS 907200-67-3)
- Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylate (CAS 730949-68-5)
- 4-(Chloromethyl)-1-isopropoxy-2-(trifluoromethyl)benzene (CAS 1215118-94-7)
- 5-(Chloromethyl)-3-(1-(4-fluorophenyl)cyclopropyl)-1,2,4-oxadiazole (CAS 1021436-47-4)
- N-(2-(Chloromethyl)-6-(trifluoromethyl)pyridin-4-yl)acetamide (CAS 1393555-15-1)
Recommended Standards
- Methyl 3-(chlorosulfonyl)-4-fluorobenzoate (CAS 1099660-67-9)
- Methyl 3-(chlorosulfonyl)-5-fluorobenzoate (CAS 1155909-75-3)
- 2-(2-Chloroethyl)-5-(3-nitrophenyl)-1,3-oxazole (CAS 1094382-62-3)
- Methyl 2-(Chlorosulfonyl)-4-fluorobenzoate (CAS 1156254-63-5)
- n-Methyl-2-nitrothiophene-3-sulfonamide (CAS 1421602-25-6)
- 4-Hydroxy phenprocoumon (CAS 55789-09-8)
- Methyl 2-(2-((6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)oxy)acetamido)benzoate (CAS 1031961-91-7)
- (2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylbutanoic acid (CAS 321524-83-8)
- 3-Amino-2-(3-methoxyphenyl)propanoic acid (CAS 774506-34-2)
- 3-Bromo-5-fluoro-4-(trifluoromethyl)pyridine (CAS 1349708-84-4)
- 2-(5-Acetamido-2-methyl-1H-imidazol-1-yl)ethyl acetate hydrochloride (CAS 1217068-35-3)
- N-(3-chlorophenyl)-2-((3-nitro-2-oxo-2H-chromen-4-yl)thio)acetamide (CAS 294853-58-0)
- tert-Butyl (R)-(7-bromo-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl)carbamate (CAS 507479-60-9)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com