Ethyl 3-(Chloromethyl)isoxazole-5-carboxylate CAS 1141427-74-8
| CAS No. | 1141427-74-8 |
| Molecular Formula | C7H8ClNO3 |
| Molecular Weight | 189.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-(Chloromethyl)isoxazole-5-carboxylate.
Ethyl 3-(Chloromethyl)isoxazole-5-carboxylate (CAS 1141427-74-8) is a high-purity analytical reference standard with the molecular formula C7H8ClNO3 and a molecular weight of 189.60 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 3-(Chloromethyl)isoxazole-5-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 189.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO3 |
| Molecular Weight | 189.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 4-(chloromethyl)-5-methylisoxazole-3-carboxylate (CAS 1177292-31-7)
- 3-(Chloromethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide (CAS 1185320-35-7)
- Ethyl 3-(chloromethyl)isoxazole-4-carboxylate (CAS 1379165-76-0)
- 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-N-methylacetamide (CAS 1384430-49-2)
- Methyl 2-[4-(chloromethyl)-1h-1,2,3-triazol-1-yl]acetate (CAS 1387563-28-1)
- 1-(Chloromethyl)-3,5-dimethyl-4-nitro-1h-pyrazole (CAS 51355-91-0)
- 2-(Chloromethyl)-4,6-dimethoxy-1,3,5-triazine (CAS 30863-39-9)
- 5-Chloromethyl-isoxazole-4-carboxylic acid ethyl ester (CAS 80196-63-0)
Recommended Standards
- 2,7-Naphthyridine-3-carbonitrile, 1-chloro- (CAS 1134580-62-3)
- Ethyl 2-Chloro-5-methyloxazole-4-carboxylate (CAS 1144520-57-9)
- 2-Chloro-5-fluoro-4-thiocyanatopyrimidine (CAS 112889-53-9)
- (S)-Methyl 1-(chlorocarbonyl)-2,3-dihydro-1H-pyrrole-2-carboxylate (CAS 103322-13-0)
- 1-((2,5-Dimethylphenyl)sulfonyl)piperidine-4-carbohydrazide (CAS 898139-97-4)
- Thiamine Impurity 54 (CAS 1124-01-2)
- 5-Aminoisoquinolin-8-ol (CAS 876480-97-6)
- 2-Nitroisophthalonitrile (CAS 51762-72-2)
- N-(azetidin-3-yl)-2-methoxyacetamide (CAS 1314908-38-7)
- 3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]Heptane-1-carboxylic acid (CAS 93257-31-9)
- 4-(2-Aminoethyl)-3-(p-tolyl)isoxazol-5(2H)-one hydrochloride (CAS 1177299-46-5)
- Methyl 6-ethyl-2-(4-((2-methylpiperidin-1-yl)sulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride (CAS 1217176-92-5)
- PPADS Tetrasodium (CAS 149017-66-3)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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