(4E)-3-(Chloromethyl)-4-[(2-chloropyridin-3-yl)-methylene]isoxazol-5(4H)-one 1142199-87-8 9247AC C10H6Cl2N2O2 CAS 1142199-87-8
| CAS No. | 1142199-87-8 |
| Molecular Formula | C10H6Cl2N2O2 |
| Molecular Weight | 257.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4E)-3-(Chloromethyl)-4-[(2-chloropyridin-3-yl)-methylene]isoxazol-5(4H)-one 1142199-87-8 9247AC C10H6Cl2N2O2.
(4E)-3-(Chloromethyl)-4-[(2-chloropyridin-3-yl)-methylene]isoxazol-5(4H)-one 1142199-87-8 9247AC C10H6Cl2N2O2 (CAS 1142199-87-8) is a high-purity analytical reference standard with the molecular formula C10H6Cl2N2O2 and a molecular weight of 257.07 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (4E)-3-(Chloromethyl)-4-[(2-chloropyridin-3-yl)-methylene]isoxazol-5(4H)-one 1142199-87-8 9247AC C10H6Cl2N2O2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6Cl2N2O2 |
| Molecular Weight | 257.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 4-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-benzoyl chloride (CAS 1119450-88-2)
- 3-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-benzoyl chloride (CAS 1119452-71-9)
- 5-(Chloromethyl)-3-(2-chlorophenethyl)-1,2,4-oxadiazole (CAS 1355171-00-4)
- 2-(Chloromethyl)-4b,5,6,7,8,8a-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one (CAS 1264045-14-8)
- 1-Benzyl-3-(chloromethyl)-1H-indazole (CAS 131427-22-0)
- 1-Benzyl-2-chloromethyl-1H-benzoimidazole (CAS 7192-00-9)
- 6-Acetyl-2-(chloromethyl)-5-methyl-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 730976-52-0)
- Benzyl (Chloromethyl) Succinate (CAS 143869-67-4)
Recommended Standards
- 5-(2,4-Dichlorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1152543-53-7)
- 5-(2,5-Dichlorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1152543-60-6)
- Methyl 2,3-dichloroquinoxaline-6-carboxylate (CAS 108258-54-4)
- 5-(3,4-Dichlorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1152543-93-5)
- 1-Cyanato-4-nitrobenzene (CAS 1129-38-0)
- (2R,5S)-5-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)tetrahydrofuran-2-carboxylic acid (CAS 779358-57-5)
- N-((trans-4-aminocyclohexyl)methyl)-5-iodo-N-methylpyridin-2-amine (CAS 1313366-18-5)
- 7-(Trifluoromethyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 779352-04-4)
- 5,8-Difluoro-2-methylquinolin-4-amine (CAS 288151-30-4)
- 4-Allyl-5-benzofuran-2-yl-4H-[1,2,4]triazole-3-thiol (CAS 573705-60-9)
- 3-Amino-3-(2-fluoro-5-nitrophenyl)propionic Acid (CAS 682803-55-0)
- N-(4-fluorobenzyl)-2-morpholinoethan-1-amine (CAS 626209-48-1)
- 2-(Cyclopentylethynyl)pyridine (CAS 865173-44-0)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com