N-(2-Methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-thiazolamineHydrobromide CAS 1143459-81-7
| CAS No. | 1143459-81-7 |
| Molecular Formula | C15H12N4O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(2-Methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-thiazolamineHydrobromide (C15H12N4O2SHBr) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(2-Methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-thiazolamineHydrobromide (CAS 1143459-81-7) is a high-purity analytical reference standard with the molecular formula C15H12N4O2SHBr and a molecular weight of 393.26 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12N4O2S HBr |
| Molecular Weight | 393.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- 5-(Diethylamino)pent-3-yn-1-ol (CAS 16454-74-3)
- Fmoc-α-Me-Phe-OH (CAS 135944-05-7)
- 4-(5-(Trifluoromethyl)pyridin-2-yl)benzonitrile (CAS 892501-99-4)
- 1-(2,6-Dimethylphenyl)-3-(4-methoxyphenyl)propan-1-one (CAS 898775-86-5)
- 6-Bromo-5-iodonicotinic acid (CAS 65799-80-6)
- 3-(2-aminoethyl)benzonitrile hydrochloride (CAS 172348-36-6)
- 2-(2-methylpropyl)pyridine (CAS 6304-24-1)
- (Z)-3-(2,4-Dibromo-5-methoxyphenyl)acrylic acid (CAS 1643592-80-6)
- 5,5''-Di-tert-butyl-5'-(3-(tert-butyl)-5-formyl-4-hydroxyphenyl)-4,4''-dihydroxy-[1,1':3',1''-terphenyl]-3,3''-dicarbaldehyde (CAS 1809653-01-7)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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