2-(((4-Hydroxy-6-isopropylthieno[2,3-d]pyrimidin-2-yl)methyl)thio)acetic acid CAS 1144489-45-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1144489-45-1
Molecular FormulaC12H14N2O3S2
Molecular Weight298.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(((4-Hydroxy-6-isopropylthieno[2,3-d]pyrimidin-2-yl)methyl)thio)acetic acid CAS 1144489-45-1 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-(((4-Hydroxy-6-isopropylthieno[2,3-d]pyrimidin-2-yl)methyl)thio)acetic acid (CAS 1144489-45-1), molecular formula C12H14N2O3S2 and molecular weight 298.38 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(((4-Hydroxy-6-isopropylthieno[2,3-d]pyrimidin-2-yl)methyl)thio)acetic acid (C12H14N2O3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H14N2O3S2
Molecular Weight298.38 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms2
Sulfur Atoms2

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