Suvorexant Impurity N40 CAS 1144509-75-0
| CAS No. | 1144509-75-0 |
| Molecular Formula | C14H18ClN3O3 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Suvorexant Impurity N40 (CAS 1144509-75-0), a pharmacopoeial impurity reference standard (molecular formula C14H18ClN3O3, MW 311.76 g/mol) used for the identification and quantification of trace impurities in APIs.
Suvorexant Impurity N40 (C14H18ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Suvorexant Impurity N40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18ClN3O3 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Suvorexant Standards
- Suvorexant Impurity 51 (CAS CATO-C4X-181251)
- Suvorexant Impurity 42 (CAS CATO-C4X-181242)
- Suvorexant impurity 27 (CAS CATO-C4X-181227)
- Suvorexant impurity 28 (CAS CATO-C4X-181228)
- Suvorexant Impurity 33 (CAS 1030377-32-2)
- Suvorexant Impurity 50 (CAS CATO-C4X-181250)
- Suvorexant impurity 25 (CAS CATO-C4X-181225)
- Suvorexant impurity 29 (CAS 218621-86-4)
Recommended Standards
- 4-Chloro-6,7-bis(2-methoxyethoxy)quinoline (CAS 1137579-56-6)
- 2-(2-Methoxyphenyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160253-73-5)
- 1-{2-[(5-chloropyridin-2-yl)(methyl)amino]acetyl}piperidine-3-carboxylic acid (CAS 1099164-84-7)
- 2-(3-Methoxyphenyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160253-75-7)
- Rotigotine EP Impurity J HCl (CAS CATO-C4X-19277)
- Topiroxostat Impurity 40 (CAS 1824131-48-7)
- Ertapenem Impurity 18 (CAS CATO-C4X-163318)
- 3-(2-Fluorophenyl)-6-(trifluoromethyl)picolinic acid (CAS 1214347-61-1)
- tert-Butyl 3-(aminomethyl)-3-methylazepane-1-carboxylate (CAS 1823794-69-9)
- Tunodafil Impurity 11 (CAS CATO-C4X-311011)
- Nirmatrelvir Impurity 2 HCl (CAS 1932411-98-7 (free base))
- 4-Chloro-n,n-diethylbutanamide (CAS 56794-28-6)
- Lucidenic acid LM1 (CAS 364622-33-3)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com