2-(Difluoromethyl)pyridine CAS 114468-01-8
| CAS No. | 114468-01-8 |
| Molecular Formula | C6H11F2N |
| Molecular Weight | 135.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 135.16 g/mol gives 2-(Difluoromethyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(Difluoromethyl)pyridine (CAS 114468-01-8), a certified reference material (molecular formula C6H11F2N, MW 135.16 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Difluoromethyl)pyridine (C6H11F2N) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Difluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H11F2N |
| Molecular Weight | 135.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)piperidine (CAS 1255859-32-5)
- 4-(Difluoromethyl)piperidine Hydrochloride (CAS 1283717-58-7)
- (2-(Difluoromethyl)cyclobutyl)methanamine (CAS 1421601-76-4)
- 1-(Difluoromethyl)cyclopentan-1-amine (CAS 1461705-26-9)
- (1-(Difluoromethyl)cyclobutyl)methanamine (CAS 1694592-93-2)
- (3-(Difluoromethyl)cyclobutyl)methanamine (CAS 1780620-26-9)
- (S)-3-(difluoromethyl)piperidine (CAS 1932019-42-5)
- (R)-3-(difluoromethyl)piperidine (CAS 1932183-72-6)
Recommended Standards
- (E)-3-(Pyridin-2-yl)prop-2-en-1-ol (CAS 113985-52-7)
- 2-Cyclopropylpyridin-4-ol (CAS 1159814-16-0)
- 6,7-Dihydro-2H-isoindol-4(5H)-one (CAS 113880-79-8)
- 5-Cyclopropylpyridin-2-ol (CAS 1159821-42-7)
- N-(2-(piperidin-4-yl)ethyl)cyclopropanamine (CAS 937648-51-6)
- 2-(3,4-Dimethylphenyl)acetonitrile (CAS 3020-06-2)
- 3-(Ethylsulfanyl)propanoic acid (CAS 7244-82-8)
- 2-Phenylquinoline-3,4-dicarboxylic acid (CAS 133505-06-3)
- Dibenzazepinone-d4 (Major) (CAS 1189706-86-2)
- 3-(3,5-Dimethoxyphenyl)-1-propene 64118-89-4 7276AE C11H14O2 (CAS 64118-89-4)
- 3-(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)propanoic acid (CAS 937605-34-0)
- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-3-morpholinopropanamide (CAS 89757-67-5)
- 2-(Azetidin-3-yloxy)-3-bromopyridine (CAS 1343093-02-6)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com