6-(2-Aminothiazol-4-yl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one CAS 114566-60-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(2-Aminothiazol-4-yl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one.

6-(2-Aminothiazol-4-yl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 114566-60-8), molecular formula C12H11N3O2S and molecular weight 261.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(2-Aminothiazol-4-yl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (C12H11N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(2-Aminothiazol-4-yl)-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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