Rocuronium Bromide Impurity 20 CAS 1145787-10-5
| CAS No. | 1145787-10-5 |
| Molecular Formula | C27H46N2O3 |
| Molecular Weight | 446.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rocuronium Bromide Impurity 20 (CAS 1145787-10-5) is a certified pharmaceutical impurity reference standard with the molecular formula C27H46N2O3 and a molecular weight of 446.67 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Rocuronium Bromide Impurity 20 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rocuronium Bromide Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H46N2O3 |
| Molecular Weight | 446.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Rocuronium Standards
- Rocuronium Impurity 18 (CAS CATO-C4X-124218)
- Rocuronium Impurity 28 (CAS CATO-C4X-124228)
- Rocuronium Impurity 38 (CAS 1252016-49-1)
- Rocuronium Impurity 39 (CAS CATO-C4X-124239)
- Rocuronium Impurity 40 (CAS CATO-C4X-124240)
- Rocuronium Impurity 63 (CAS CATO-C4X-124263)
- Rocuronium Bromide Impurity 64 (CAS CATO-C4X-124264)
- Rocuronium EP Impurity G (CAS 119302-20-4)
Recommended Standards
- tert-Butyl (3-bromo-4-chloro-5,6-difluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate (CAS 2245358-38-5)
- VU 0483605 (CAS 1623101-11-0)
- Di-Isodecyl Phthalate (CAS 68515-49-1)
- Phthalic Acid, Bis-Isodecyl Ester (CAS 26761-40-0)
- Zanamivir EP Impurity F(HCl) (CAS 4023-02-3)
- Oseltamivir impurity 270 (CAS 3044729-56-5)
- Entecavir EP Impurity C (CAS 2204369-23-1)
- 2-(Benzofuran-2-yl)-4-isobutylthiazole-5-carboxylic acid (CAS 1778623-14-5)
- (cyclopropylmethyl)(1-phenylethyl)amine (CAS 356539-54-3)
- 4,6-Dichloro-2-(piperidin-1-yl)pyrimidine (CAS 7038-67-7)
- 5-(Furan-2-yl)-n-methyl-1,2-oxazole-3-carboxamide (CAS 1343867-60-6)
- 2-(2-(2-(4-Bromophenoxy)acetyl)hydrazine-1-carbonyl)benzoic acid (CAS 355809-53-9)
- 1-(4-Methoxyphenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydro-1H-indol-4-one (CAS 163083-10-1)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com