3-(4-Chloro-2-fluorophenyl)-4-methyl-1h-pyrazol-5-amine CAS 1146218-11-2
| CAS No. | 1146218-11-2 |
| Molecular Formula | C10H9ClFN3 |
| Molecular Weight | 225.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Chloro-2-fluorophenyl)-4-methyl-1h-pyrazol-5-amine (C10H9ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(4-Chloro-2-fluorophenyl)-4-methyl-1h-pyrazol-5-amine (CAS 1146218-11-2), a certified reference material (molecular formula C10H9ClFN3, MW 225.65 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClFN3 |
| Molecular Weight | 225.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-1-(2-fluorobenzyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1001757-51-2)
- 4-Chloro-1-[(4-fluorophenyl)methyl]-1h-pyrazol-3-amine (CAS 1001757-53-4)
- 4-Chloro-1-(3-fluorobenzyl)-1H-pyrazol-3-amine (CAS 1001757-55-6)
- 1-[(2-Chloro-4-fluorophenyl)methyl]-1H-pyrazol-4-amine (CAS 1002033-29-5)
- (R)-1-(2-Chloro-8-fluoroquinolin-3-yl)ethanol, 97% (CAS 1065481-27-7)
- (R)-1-(2-chloro-7-fluoroquinolin-3-yl)ethan-1-ol (CAS 1065483-17-1)
- 3-(5-Chloro-2-fluorophenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1152666-84-6)
- 3-(2-Chloro-4-fluorophenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1152708-48-9)
Recommended Standards
- 2-(1-Chloroethyl)-5-(4-fluorophenyl)oxazole (CAS 1094318-38-3)
- 4-Amino-1-(2-chloro-4-fluorobenzyl)pyrazole Hydrochloride (CAS 1147222-53-4)
- N-((1H-pyrazol-3-yl)methyl)-3-chloro-4-fluoroaniline (CAS 1156320-54-5)
- (5-(3-Chloro-4-fluorophenyl)-1H-imidazol-2-yl)methanamine (CAS 1156713-62-0)
- N-(4-amino-2-methylphenyl)-2,2-dimethylbutanamide (CAS 946736-77-2)
- 3-(4-Methoxyphenyl)-5-(piperidin-4-yl)-1,2,4-oxadiazole (CAS 276237-02-6)
- tert-Butyl (2-formylbenzofuran-4-yl)carbamate (CAS 503621-02-1)
- 1,4-Dimethylquinolin-2(1H)-one (CAS 2584-47-6)
- {1-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]piperidin-4-yl}acetic acid (CAS 1171599-18-0)
- Methyl 3-(7-chloro-6-methoxy-4-oxoquinolin-1(4H)-yl)propanoate (CAS 1315352-76-1)
- (S)-N,N-dimethylpiperidin-3-amine dihydrochloride (CAS 1630082-61-9)
- 2-{2-Cyclopropyl-7-fluoro-1H-benzo[d]imidazol-1-yl}acetic acid (CAS 1509413-45-9)
- 5-Bromo-2-(1H-pyrazol-4-yl)aniline (CAS 1820683-34-8)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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