Atorvastatin EP Impurity M CAS 1146977-93-6
| CAS No. | 1146977-93-6 |
| Molecular Formula | C35H39FN2O5 |
| Molecular Weight | 586.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Atorvastatin EP Impurity M (C35H39FN2O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Atorvastatin EP Impurity M (CAS 1146977-93-6) is a certified pharmaceutical impurity reference standard with the molecular formula C35H39FN2O5 and a molecular weight of 586.69 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Atorvastatin EP Impurity M under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H39FN2O5 |
| Molecular Weight | 586.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Lactam Phenanthrene Methyl Ester(Mixture of Diastereomers) (CAS 906552-20-3)
- Atorvastatin Impurity 137 (CAS CATO-C4X-1132137)
- Atorvastatin lactam methyl ester (CAS 1795790-02-1)
- Atorvastatin Impurity 110 (CAS 887470-43-1)
- Atorvastatin Impurity 129 (CAS 873950-17-5)
- Atorvastatin Impurity 156 (CAS CATO-C4X-1132156)
- Atorvastatin Cyclic (Fluorophenyl) Impurity (CAS 873950-18-6)
- Atorvastatin Impurity 105 (CAS CATO-C4X-1132105)
Recommended Standards
- Omacycline Impurity 6 (CAS 1075240-42-4)
- Razuprotafib (CAS 1008510-37-9)
- Omadacycline Impurity 28 (CAS CATO-C4X-285728)
- 4-Methoxy-N,N-dimethyl-3-[[[3-[[2-[(3-methylbenzoyl)amino]ethyl]amino]phenyl]amino]sulfonyl]-[1,1-biphenyl]-3-carboxamide (CAS 1796565-52-0)
- Carbazochrome Impurity 12 (CAS CATO-C4X-229112)
- BB-K 6 Disulfate Salt (Amikacin EP Impurity E Disulfate) (CAS 50866-72-3(Free Base))
- Etoposide Impurity 32 (CAS CATO-C4X-202432)
- 4-(4-Methylphenylsulfonyl)semicarbazidehydrochloride (CAS 206761-77-5)
- N-Methyl-N-(5-(methylthio)furan-2-yl)pivalamide (CAS 408500-84-5)
- 3-{2,5-dimethyl-7-oxo-3-phenyl-4h,7h-pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid (CAS 878417-25-5)
- 2-Chloro-N-(2,6-dichlorophenyl)benzamide (CAS 200807-45-0)
- 1-[(1-methyl-1h-1,3-benzodiazol-2-yl)methyl]-1h-pyrazol-4-amine (CAS 1304872-08-9)
- 2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethyl-6-methylphenyl)acetamide (CAS 510713-62-9)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com