((2-Bromo-6-nitrobenzyl)oxy)(tert-butyl)dimethylsilane CAS 1147531-02-9
| CAS No. | 1147531-02-9 |
| Molecular Formula | C13H20BrNO3Si |
| Molecular Weight | 346.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including ((2-Bromo-6-nitrobenzyl)oxy)(tert-butyl)dimethylsilane.
((2-Bromo-6-nitrobenzyl)oxy)(tert-butyl)dimethylsilane (CAS 1147531-02-9) is a high-purity analytical reference standard with the molecular formula C13H20BrNO3Si and a molecular weight of 346.29 g/mol.
The molecular framework of ((2-Bromo-6-nitrobenzyl)oxy)(tert-butyl)dimethylsilane (C13H20BrNO3Si) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), ((2-Bromo-6-nitrobenzyl)oxy)(tert-butyl)dimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20BrNO3Si |
| Molecular Weight | 346.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Potassium (3-Bromophenyl)trifluoroborate (CAS 374564-34-8)
- 120814-48-4 (Pro7)-Neurokinin B MFCD00167604 (CAS 120814-48-4)
- (1R,2R,4S)-rel-tert-Butyl 2-hydroxy-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 152533-46-5)
- 4-Chloro-2-((4-(tetrahydro-2H-pyran-4-yl)piperidin-1-yl)methyl)phenol (CAS 865076-11-5)
- 5-Amino-2-methyl-1,2-dihydro-3H-1,2,4-triazole-3-thione (CAS 37634-01-8)
- 4',5'-Dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 2320-96-9)
- 2-Chloro-N-cyclopropylbenzamide (CAS 88229-17-8)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
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