1-(2-Fluorophenyl)piperidin-4-one CAS 115012-46-9
| CAS No. | 115012-46-9 |
| Molecular Formula | C11H12FNO |
| Molecular Weight | 193.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Fluorophenyl)piperidin-4-one.
1-(2-Fluorophenyl)piperidin-4-one (CAS 115012-46-9), molecular formula C11H12FNO and molecular weight 193.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Fluorophenyl)piperidin-4-one (C11H12FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Fluorophenyl)piperidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12FNO |
| Molecular Weight | 193.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 1-(4-Fluorophenyl)piperidin-4-one (CAS 116247-98-4)
- 1-(4-Fluorophenyl)-N-methylcyclopropane-1-carboxamide (CAS 1210889-55-6)
- 1-(2-Fluorophenyl)piperidin-2-one (CAS 1226150-23-7)
- 1-(3-Fluorophenyl)piperidin-2-one (CAS 1226406-37-6)
- (3-Fluorophenyl)(pyrrolidin-3-yl)methanone (CAS 1315593-36-2)
- 2-(4-Fluorophenyl)pyrrolidine-1-carbaldehyde (CAS 1355178-73-2)
- 1-(2-Fluorophenyl)-N-methylcyclopropane-1-carboxamide (CAS 1357726-25-0)
- 4-(3-Fluorophenyl)-4-methylpyrrolidin-2-one (CAS 1479611-24-9)
Recommended Standards
- 2-[cyclopropyl(methyl)amino]-5-fluorobenzaldehyde (CAS 1096786-01-4)
- 5-(N-Ethyl-N-isopropyl) Amiloride (CAS 1154-25-2)
- 1-(5-Fluoro-3-methyl-1-benzofuran-2-yl)ethan-1-amine (CAS 1094254-11-1)
- 2-(Vinylsulfonyl)benzonitrile (CAS 1154395-71-7)
- 2-3-6-2-3-4-6-Hepta-O-acetyl-β-lactosyl azide (CAS 30854-62-7)
- (S)-2-Amino-N-((1-benzylpyrrolidin-2-yl)methyl)-N-cyclopropylacetamide (CAS 1353996-76-5)
- 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidine-4-carboxylic acid (CAS 1261231-45-1)
- N-(tert-butoxycarbonyl)-n,o-dimethyl-l-threonine (CAS 136092-75-6)
- (R)-Xyl-SpiroSAP-Ph (CAS 1809609-39-9)
- 2,5-Dioxopyrrolidin-1-yl 4-hydroxybenzoate (CAS 70074-31-6)
- 150111-89-0 ACMC-20n5ws Phosphine,1,1'-(1,4-butanediyl)bis[1,1-bis(1,1-dimethylethyl)- (CAS 150111-89-0)
- N-Methyl-4-(methylamino)-3-nitrobenzenesulfonamide (CAS 68502-28-3)
- 1-{3-[(3,4-Dichlorobenzyl)sulfonyl]-2-hydroxypropyl}-2-pyrrolidinone (CAS 400086-36-4)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
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