tert-Butyl 2-chloro-8-methyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate CAS 1151665-38-1
| CAS No. | 1151665-38-1 |
| Molecular Formula | C14H19ClN2O2 |
| Molecular Weight | 282.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
tert-Butyl 2-chloro-8-methyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 1151665-38-1) is a high-purity analytical reference standard with the molecular formula C14H19ClN2O2 and a molecular weight of 282.77 g/mol.
The molecular framework of tert-Butyl 2-chloro-8-methyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (C14H19ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), tert-Butyl 2-chloro-8-methyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19ClN2O2 |
| Molecular Weight | 282.77 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-(2-chloropropanamido)-N,N-diethylbenzamide (CAS 1098347-63-7)
- 4-chloro-3,5-bis(4-methylphenyl)-1h-pyraZole (CAS 1159988-47-2)
- 1-(4-(2-(2-Chlorophenyl)-2-hydroxyethyl)piperazin-1-yl)ethan-1-one (CAS 1082806-45-8)
- 1-(5-Chloro-1-(3-ethoxypropyl)-1H-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 1243803-67-9)
- 1-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanol (CAS 61821-85-0)
- 2-Chloro-N-(3-(4-chlorophenyl)-1-methyl-1h-pyrazol-5-yl)acetamide (CAS 655235-37-3)
- 4-(Chloromethyl)-2-isopropyloxazole (CAS 39624-97-0)
- N-(2,2-dimethyl-4-oxochroman-6-yl)acetamide (CAS 186774-61-8)
- n-(4-Chlorophenyl)-2-(propylamino)acetamide (CAS 1021230-54-5)
- Fenfuram Impurity 7 (CAS 28562-70-1)
- {[4-formyl-3-methyl-1-(4-methylbenzyl)-1H-pyrazol-5-yl]thio}acetic acid (CAS 956568-49-3)
- 2-(Dodecylsulfanyl)ethan-1-ol (CAS 1462-55-1)
- 1-(3-Bromophenyl)cyclopentan-1-ol (CAS 210826-69-0)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com