Tezacaftor CAS 1152311-62-0
| CAS No. | 1152311-62-0 |
| Molecular Formula | C26H27F3N2O6 |
| Molecular Weight | 520.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tezacaftor (C26H27F3N2O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Tezacaftor (CAS 1152311-62-0) is a high-purity analytical reference standard with the molecular formula C26H27F3N2O6 and a molecular weight of 520.50 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Tezacaftor meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H27F3N2O6 |
| Molecular Weight | 520.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tezacaftor Standards
- Tezacaftor (Racemate) (CAS 1226709-85-8)
- Tezacaftor Impurity C34 (CAS 1419101-35-1)
- (S)-Tezacaftor (CAS 1152311-99-3)
- Tezacaftor Metabolite M1 (Mixture of Diastereomers) (CAS 1432656-97-7)
- Tezacaftor Metabolite M1 (CAS 1432657-04-9)
- Tezacaftor Impurity 1 (CAS 2229860-93-7)
- Tezacaftor Impurity C28 (CAS 1294504-68-9)
Recommended Standards
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Why CATO?
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