4-Amino-5-(5-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol CAS 1152598-88-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-5-(5-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol.

4-Amino-5-(5-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol (CAS 1152598-88-3), molecular formula C6H5BrN4S2 and molecular weight 277.16 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, sulfur-containing functionality, bromine substitution, an aromatic ring system, 4-Amino-5-(5-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 277.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Amino-5-(5-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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