8-Bromo-2-chloro-7-fluoroquinoline CAS 1152781-66-2
| CAS No. | 1152781-66-2 |
| Molecular Formula | C9H4BrClFN |
| Molecular Weight | 260.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Bromo-2-chloro-7-fluoroquinoline (CAS 1152781-66-2) is a high-purity analytical reference standard with the molecular formula C9H4BrClFN and a molecular weight of 260.49 g/mol.
Based on its molecular formula C9H4BrClFN, 8-Bromo-2-chloro-7-fluoroquinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 260.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 8-Bromo-2-chloro-7-fluoroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4BrClFN |
| Molecular Weight | 260.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 6-Bromo-4-chloro-8-fluoroquinoline (CAS 1019016-66-0)
- 8-Bromo-4-chloro-6-fluoroquinoline (CAS 1019016-73-9)
- 8-Bromo-4-chloro-5-fluoroquinoline (CAS 1065093-11-9)
- 5-Bromo-4-chloro-8-fluoroquinoline (CAS 1065093-13-1)
- 3-Bromo-4-chloro-7-fluoroquinoline (CAS 1204810-31-0)
- 4-Bromo-3-chloro-7-fluoroquinoline (CAS 1208814-10-1)
- 4-Bromo-3-chloro-8-fluoroquinoline (CAS 1211659-63-0)
- 5-Bromo-2-chloro-8-fluoroquinoline (CAS 1215767-73-9)
Recommended Standards
- 8-Bromo-2-chloropyrido[3,4-b]pyrazin-7-ol (CAS 2377496-00-7)
- 6-Bromo-2-chloro-8-fluoroquinoline (CAS 1215767-81-9)
- 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine-5-carbaldehyde (CAS 938191-84-5)
- 8-bromo-2-chloro-6-fluoro-quinoline (CAS 1342486-86-5)
- 2-Chloro-5-methanesulfonylbenzene-1-sulfonamide (CAS 3544-47-6)
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