2-[4-(2,2,2-trifluoroethanesulfonyl)phenyl]acetic acid CAS 1153070-21-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1153070-21-3
Molecular FormulaC10H9F3O4S
Molecular Weight282.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[4-(2,2,2-trifluoroethanesulfonyl)phenyl]acetic acid CAS 1153070-21-3 chemical structure

Description

CATO supplies 2-[4-(2,2,2-trifluoroethanesulfonyl)phenyl]acetic acid (CAS 1153070-21-3), a certified reference material (molecular formula C10H9F3O4S, MW 282.24 g/mol) for analytical method development and quality control.

The molecular framework of 2-[4-(2,2,2-trifluoroethanesulfonyl)phenyl]acetic acid (C10H9F3O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-[4-(2,2,2-trifluoroethanesulfonyl)phenyl]acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H9F3O4S
Molecular Weight282.24 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Sulfur Atoms1

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